Major Depressive Disorder 2010



Classification of the disorder

Major depression is in MOOD DISORDER category.

Definition and Description of the Disorder (who is most likely to get it, what is it, when do people get it).
Major depressive disorder is a mood disorder in which a person, for no apparent reason, experiences two or more weeks of depressed moods, feelings of worthlessness, and diminished interest or pleasure in most activities.1

It mostly occurs in age between 24 to 44. The fifty percent of people experience first episode at about 40s but it's shifting down to 30s. Teenager depression is increasing with evidence of suicide rates. Also occurs in men 10% an 20% in women. Due to hormone difference, women is riskier in danger of depression.

A Complete List of symptoms 3
  • Depressed mood most of the day, nearly every day, as indicated by either subjective report (e.g., feeling sad or empty) or observation made by others (e.g., appears tearful). (In children and adolescents, this may be characterized as an irritable mood.)
  • Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day
  • Significant weight loss when not dieting or weight gain (e.g., a change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day.
  • Insomnia or hypersomnia nearly every day
  • Psychomotor agitation or retardation nearly every day
  • Fatigue or loss of energy nearly every day
  • Feelings of worthlessness or excessive or inappropriate guilt nearly every day
  • Diminished ability to think or concentrate, or indecisiveness, nearly every day
  • Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan, or a suicide attempt or a specific plan for committing suicide

Any Known Causes 2
Major depressive disorder is caused by combination of brain chemistry, family history and the environment. It's not yet discovered which of these factor is the major cause but unstable level of neurotransmitters such as norepinephrine, serotonin and dopamine is closely related to the depression. Neurotransmitter clearly decides the mood and pleasure.

Therapies and Treatments 4
It’s the most critical decision a doctor makes whether to hospitalize a patient. A clear reason of hospitalization are risk of suicide or homicide, reduce in care for food, clothing and shelter and need of medical diagnostic procedures.

With antidepressant the suicide rate and hospitalization rate decrease dramatically. However the problem is that patients don’t stay on their medication long enough that they fail.

One of the best procedure is combination of antidepressant and psychotherapy. Psychotherapy can help patient to ease the stress that can trigger further illness and help with the illness.

Interpersonal therapy
This therapy believes that disrupted social and personal relationships cause depression. The therapist helps patient to understand the illness and how depression and interpersonal issues are related.

A Case Study 5
Case Study, Part I: Karen Complains of Pain and Sadness Karen, 32 years of age, presents to her primary care provider with complaint of chronic pain related to a previous back injury. She appears quiet and shy. In addition to the constant low backache, she reports feeling sad most days and has lost considerable interest in many of the activities that she once enjoyed, such as skiing and painting. She describes having difficulty concentrating at work and feeling guilty about many things that she does and has not done. In addition, she is complaining of having a poor appetite and having problems staying asleep. She reports that these symptoms are reduced on days she has less pain, but over the past 2 weeks, her symptoms have remained constant.

Related Disorder 6
Dythymic disorder
Seasonal affective disorder

Atypical Depression
Bipolar Disorder
Athletes with Depression
Antepartum Depression
Postpartum Depression

Additional Information

Pictures and Videos

Major Depression Disorder 2010 - The Neuron8Major Depression Disorder 2010 - The Neuron9

  1. Myers, D.G. (2004). Psychology. New York: New York:Worth Publishers.
  2. Major Depressive Disorder - Cause & Risk Factors. Retrieved March 18, 2010, from Web site:
  3. Psych Central: Depression and Major Depression Disorder Symptoms. Retrieved March 18, 2010, from PsychCentral Web site:
  4. Treatment of Major Depression - Healthyplace. Retrieved March 18, 2010, from Healthyplace Web site:
  5. Treatment Strategies for Major Depressive. Retrieved March 18, 2010, from Medscape Today Web site:
  6. Major Depression. Retrieved March 18, 2010, from Family Practice Web site:
  7. Major Depressive Disorder. Retrieved March 18, 2010, from Youtube Web site:
  8. Las Vegas personal Injury Attorney and Lawyer. Retrieved March 18, 2010, from Brain & Spine Injury Blog Web site:
  9. Major Depressive Disorder - How To Tell If You're Suffering Or Just Having A Sad Day. Retrieved March 18, 2010, from A Disease A Day Web site:

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